|
6. References Abrieu, A., Magnaghi-Jaulin, L., Kahana, J.A., Peter, M., Castro, A., Vigneron, S., Lorca, T., Cleveland, D.W., and Labbe, J.C. (2001). Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint. Cell 106, 83-93. Alvi, A.J., Austen, B., Weston, V.J., Fegan, C., MacCallum, D., Gianella-Borradori, A., Lane, D.P., Hubank, M., Powell, J.E., Wei, W., et al. (2005). A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival. Blood 105, 4484-4491. Asiedu, C., Biggs, J., Lilly, M., and Kraft, A.S. (1995). Inhibition of leukemic cell growth by the protein kinase C activator bryostatin 1 correlates with the dephosphorylation of cyclin-dependent kinase 2. Cancer Res 55, 3716-3720. Bakhoum, S.F., Genovese, G., and Compton, D.A. (2009). Deviant kinetochore microtubule dynamics underlie chromosomal instability. Curr Biol 19, 1937-1942. Boss, D.S., Schwartz, G.K., Middleton, M.R., Amakye, D.D., Swaisland, H., Midgley, R.S., Ranson, M., Danson, S., Calvert, H., Plummer, R., et al. (2010). Safety, tolerability, pharmacokinetics and pharmacodynamics of the oral cyclin-dependent kinase inhibitor AZD5438 when administered at intermittent and continuous dosing schedules in patients with advanced solid tumours. Ann Oncol 21, 884-894. Cheeseman, I.M., Chappie, J.S., Wilson-Kubalek, E.M., and Desai, A. (2006). The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell 127, 983-997. Chen, D.S. (2010). Toward elimination and eradication of hepatitis B. J Gastroenterol Hepatol 25, 19-25. Chen, K.F., Chen, H.L., Tai, W.T., Feng, W.C., Hsu, C.H., Chen, P.J., and Cheng, A.L. (2011). Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells. J Pharmacol Exp Ther 337, 155-161. De Antoni, A., Pearson, C.G., Cimini, D., Canman, J.C., Sala, V., Nezi, L., Mapelli, M., Sironi, L., Faretta, M., Salmon, E.D., et al. (2005). The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint. Curr Biol 15, 214-225. Dickson, M.A., and Schwartz, G.K. (2009). Development of cell-cycle inhibitors for cancer therapy. Current oncology 16, 36-43. Fang, G., Yu, H., and Kirschner, M.W. (1998). The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation. Genes Dev 12, 1871-1883. Finn, R.S., Crown, J.P., Lang, I., Boer, K., Bondarenko, I.M., Kulyk, S.O., Ettl, J., Patel, R., Pinter, T., Schmidt, M., et al. (2015). The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study. Lancet Oncol 16, 25-35. Foley, E.A., Maldonado, M., and Kapoor, T.M. (2011). Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase. Nat Cell Biol 13, 1265-1271. Fry, D.W., Harvey, P.J., Keller, P.R., Elliott, W.L., Meade, M., Trachet, E., Albassam, M., Zheng, X., Leopold, W.R., Pryer, N.K., et al. (2004). Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts. Mol Cancer Ther 3, 1427-1438. Hahntow, I.N., Schneller, F., Oelsner, M., Weick, K., Ringshausen, I., Fend, F., Peschel, C., and Decker, T. (2004). Cyclin-dependent kinase inhibitor Roscovitine induces apoptosis in chronic lymphocytic leukemia cells. Leukemia 18, 747-755. Hara, K., Zheng, G., Qu, Q., Liu, H., Ouyang, Z., Chen, Z., Tomchick, D.R., and Yu, H. (2014). Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion. Nat Struct Mol Biol 21, 864-870. Hauf, S., Roitinger, E., Koch, B., Dittrich, C.M., Mechtler, K., and Peters, J.M. (2005). Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2. PLoS Biol 3, e69. Hauf, S., Waizenegger, I.C., and Peters, J.M. (2001). Cohesin cleavage by separase required for anaphase and cytokinesis in human cells. Science 293, 1320-1323. Holland, A.J., and Cleveland, D.W. (2009). Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis. Nat Rev Mol Cell Biol 10, 478-487. Horvat, R.T. (2011). Diagnostic and Clinical Relevance of HBV Mutations. Labmedicine 42, 488-496. Huang, M., and Liu, G. (1999). The study of innate drug resistance of human hepatocellular carcinoma Bel7402 cell line. Cancer Lett 135, 97-105. Huang, S.N., and Chisari, F.V. (1995). Strong, sustained hepatocellular proliferation precedes hepatocarcinogenesis in hepatitis B surface antigen transgenic mice. Hepatology 21, 620-626. Hwang, L.H., Lau, L.F., Smith, D.L., Mistrot, C.A., Hardwick, K.G., Hwang, E.S., Amon, A., and Murray, A.W. (1998). Budding yeast Cdc20: a target of the spindle checkpoint. Science 279, 1041-1044. Iwaizumi, M., Shinmura, K., Mori, H., Yamada, H., Suzuki, M., Kitayama, Y., Igarashi, H., Nakamura, T., Suzuki, H., Watanabe, Y., et al. (2009). Human Sgo1 downregulation leads to chromosomal instability in colorectal cancer. Gut 58, 249-260. Izawa, D., and Pines, J. (2015). The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C. Nature 517, 631-634. Jayson, G.C., Crowther, D., Prendiville, J., McGown, A.T., Scheid, C., Stern, P., Young, R., Brenchley, P., Chang, J., Owens, S., et al. (1995). A phase I trial of bryostatin 1 in patients with advanced malignancy using a 24 hour intravenous infusion. Br J Cancer 72, 461-468. Jiang, X.R., Jimenez, G., Chang, E., Frolkis, M., Kusler, B., Sage, M., Beeche, M., Bodnar, A.G., Wahl, G.M., Tlsty, T.D., et al. (1999). Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nat Genet 21, 111-114. Kahyo, T., Iwaizumi, M., Shinmura, K., Matsuura, S., Nakamura, T., Watanabe, Y., Yamada, H., and Sugimura, H. (2011). A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion. Oncogene. Kallio, M.J., McCleland, M.L., Stukenberg, P.T., and Gorbsky, G.J. (2002). Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis. Curr Biol 12, 900-905. Kang, J., Chaudhary, J., Dong, H., Kim, S., Brautigam, C.A., and Yu, H. (2011). Mitotic Centromeric Targeting of HP1 and Its Binding to Sgo1 Are Dispensable for Sister-Chromatid Cohesion in Human Cells. Mol Biol Cell. Kato, A., Miyazaki, M., Ambiru, S., Yoshitomi, H., Ito, H., Nakagawa, K., Shimizu, H., Yokosuka, O., and Nakajima, N. (2001). Multidrug resistance gene (MDR-1) expression as a useful prognostic factor in patients with human hepatocellular carcinoma after surgical resection. J Surg Oncol 78, 110-115. Kim, E.H., Kim, S.U., Shin, D.Y., and Choi, K.S. (2004). Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP. Oncogene 23, 446-456. Kitajima, T.S., Hauf, S., Ohsugi, M., Yamamoto, T., and Watanabe, Y. (2005). Human Bub1 defines the persistent cohesion site along the mitotic chromosome by affecting Shugoshin localization. Curr Biol 15, 353-359. Kitajima, T.S., Sakuno, T., Ishiguro, K., Iemura, S., Natsume, T., Kawashima, S.A., and Watanabe, Y. (2006). Shugoshin collaborates with protein phosphatase 2A to protect cohesin. Nature 441, 46-52. Landry, J.J., Pyl, P.T., Rausch, T., Zichner, T., Tekkedil, M.M., Stutz, A.M., Jauch, A., Aiyar, R.S., Pau, G., Delhomme, N., et al. (2013). The genomic and transcriptomic landscape of a HeLa cell line. G3 (Bethesda) 3, 1213-1224. Lavanchy, D. (2005). Worldwide epidemiology of HBV infection, disease burden, and vaccine prevention. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 34 Suppl 1, S1-3. Lee, J., Kitajima, T.S., Tanno, Y., Yoshida, K., Morita, T., Miyano, T., Miyake, M., and Watanabe, Y. (2008). Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells. Nat Cell Biol 10, 42-52. Liu, D., Vader, G., Vromans, M.J., Lampson, M.A., and Lens, S.M. (2009). Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates. Science 323, 1350-1353. Liu, H., Jia, L., and Yu, H. (2013). Phospho-H2A and cohesin specify distinct tension-regulated Sgo1 pools at kinetochores and inner centromeres. Curr Biol 23, 1927-1933. Liu, H., Rankin, S., and Yu, H. (2012). Phosphorylation-enabled binding of SGO1-PP2A to cohesin protects sororin and centromeric cohesion during mitosis. Nat Cell Biol. Llovet, J.M., Ricci, S., Mazzaferro, V., Hilgard, P., Gane, E., Blanc, J.F., de Oliveira, A.C., Santoro, A., Raoul, J.L., Forner, A., et al. (2008). Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 359, 378-390. Locarnini, S. (2004). Molecular virology of hepatitis B virus. Seminars in liver disease 24 Suppl 1, 3-10. Longley, D.B., and Johnston, P.G. (2005). Molecular mechanisms of drug resistance. J Pathol 205, 275-292. Losada, A., Hirano, M., and Hirano, T. (1998). Identification of Xenopus SMC protein complexes required for sister chromatid cohesion. Genes Dev 12, 1986-1997. Losada, A., Hirano, M., and Hirano, T. (2002). Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis. Genes Dev 16, 3004-3016. MacCallum, D.E., Melville, J., Frame, S., Watt, K., Anderson, S., Gianella-Borradori, A., Lane, D.P., and Green, S.R. (2005). Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1. Cancer Res 65, 5399-5407. Abrieu, A., Magnaghi-Jaulin, L., Kahana, J.A., Peter, M., Castro, A., Vigneron, S., Lorca, T., Cleveland, D.W., and Labbe, J.C. (2001). Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint. Cell 106, 83-93. Alvi, A.J., Austen, B., Weston, V.J., Fegan, C., MacCallum, D., Gianella-Borradori, A., Lane, D.P., Hubank, M., Powell, J.E., Wei, W., et al. (2005). A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival. Blood 105, 4484-4491. Asiedu, C., Biggs, J., Lilly, M., and Kraft, A.S. (1995). Inhibition of leukemic cell growth by the protein kinase C activator bryostatin 1 correlates with the dephosphorylation of cyclin-dependent kinase 2. Cancer Res 55, 3716-3720. Bakhoum, S.F., Genovese, G., and Compton, D.A. (2009). Deviant kinetochore microtubule dynamics underlie chromosomal instability. Curr Biol 19, 1937-1942. Boss, D.S., Schwartz, G.K., Middleton, M.R., Amakye, D.D., Swaisland, H., Midgley, R.S., Ranson, M., Danson, S., Calvert, H., Plummer, R., et al. (2010). Safety, tolerability, pharmacokinetics and pharmacodynamics of the oral cyclin-dependent kinase inhibitor AZD5438 when administered at intermittent and continuous dosing schedules in patients with advanced solid tumours. Ann Oncol 21, 884-894. Cheeseman, I.M., Chappie, J.S., Wilson-Kubalek, E.M., and Desai, A. (2006). The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell 127, 983-997. Chen, D.S. (2010). Toward elimination and eradication of hepatitis B. J Gastroenterol Hepatol 25, 19-25. Chen, K.F., Chen, H.L., Tai, W.T., Feng, W.C., Hsu, C.H., Chen, P.J., and Cheng, A.L. (2011). Activation of phosphatidylinositol 3-kinase/Akt signaling pathway mediates acquired resistance to sorafenib in hepatocellular carcinoma cells. J Pharmacol Exp Ther 337, 155-161. De Antoni, A., Pearson, C.G., Cimini, D., Canman, J.C., Sala, V., Nezi, L., Mapelli, M., Sironi, L., Faretta, M., Salmon, E.D., et al. (2005). The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint. Curr Biol 15, 214-225. Dickson, M.A., and Schwartz, G.K. (2009). Development of cell-cycle inhibitors for cancer therapy. Current oncology 16, 36-43. Fang, G., Yu, H., and Kirschner, M.W. (1998). The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation. Genes Dev 12, 1871-1883. Finn, R.S., Crown, J.P., Lang, I., Boer, K., Bondarenko, I.M., Kulyk, S.O., Ettl, J., Patel, R., Pinter, T., Schmidt, M., et al. (2015). The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study. Lancet Oncol 16, 25-35. Foley, E.A., Maldonado, M., and Kapoor, T.M. (2011). Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase. Nat Cell Biol 13, 1265-1271. Fry, D.W., Harvey, P.J., Keller, P.R., Elliott, W.L., Meade, M., Trachet, E., Albassam, M., Zheng, X., Leopold, W.R., Pryer, N.K., et al. (2004). Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts. Mol Cancer Ther 3, 1427-1438. Hahntow, I.N., Schneller, F., Oelsner, M., Weick, K., Ringshausen, I., Fend, F., Peschel, C., and Decker, T. (2004). Cyclin-dependent kinase inhibitor Roscovitine induces apoptosis in chronic lymphocytic leukemia cells. Leukemia 18, 747-755. Hara, K., Zheng, G., Qu, Q., Liu, H., Ouyang, Z., Chen, Z., Tomchick, D.R., and Yu, H. (2014). Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion. Nat Struct Mol Biol 21, 864-870. Hauf, S., Roitinger, E., Koch, B., Dittrich, C.M., Mechtler, K., and Peters, J.M. (2005). Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2. PLoS Biol 3, e69. Hauf, S., Waizenegger, I.C., and Peters, J.M. (2001). Cohesin cleavage by separase required for anaphase and cytokinesis in human cells. Science 293, 1320-1323. Horvat, R.T. (2011). Diagnostic and Clinical Relevance of HBV Mutations. Labmedicine 42, 488-496. Huang, M., and Liu, G. (1999). The study of innate drug resistance of human hepatocellular carcinoma Bel7402 cell line. Cancer Lett 135, 97-105. Huang, S.N., and Chisari, F.V. (1995). Strong, sustained hepatocellular proliferation precedes hepatocarcinogenesis in hepatitis B surface antigen transgenic mice. Hepatology 21, 620-626. Hwang, L.H., Lau, L.F., Smith, D.L., Mistrot, C.A., Hardwick, K.G., Hwang, E.S., Amon, A., and Murray, A.W. (1998). Budding yeast Cdc20: a target of the spindle checkpoint. Science 279, 1041-1044. Iwaizumi, M., Shinmura, K., Mori, H., Yamada, H., Suzuki, M., Kitayama, Y., Igarashi, H., Nakamura, T., Suzuki, H., Watanabe, Y., et al. (2009). Human Sgo1 downregulation leads to chromosomal instability in colorectal cancer. Gut 58, 249-260. Izawa, D., and Pines, J. (2015). The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C. Nature 517, 631-634. Jayson, G.C., Crowther, D., Prendiville, J., McGown, A.T., Scheid, C., Stern, P., Young, R., Brenchley, P., Chang, J., Owens, S., et al. (1995). A phase I trial of bryostatin 1 in patients with advanced malignancy using a 24 hour intravenous infusion. Br J Cancer 72, 461-468. Jiang, X.R., Jimenez, G., Chang, E., Frolkis, M., Kusler, B., Sage, M., Beeche, M., Bodnar, A.G., Wahl, G.M., Tlsty, T.D., et al. (1999). Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype. Nat Genet 21, 111-114. Kahyo, T., Iwaizumi, M., Shinmura, K., Matsuura, S., Nakamura, T., Watanabe, Y., Yamada, H., and Sugimura, H. (2011). A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion. Oncogene. Kallio, M.J., McCleland, M.L., Stukenberg, P.T., and Gorbsky, G.J. (2002). Inhibition of aurora B kinase blocks chromosome segregation, overrides the spindle checkpoint, and perturbs microtubule dynamics in mitosis. Curr Biol 12, 900-905. Kang, J., Chaudhary, J., Dong, H., Kim, S., Brautigam, C.A., and Yu, H. (2011). Mitotic Centromeric Targeting of HP1 and Its Binding to Sgo1 Are Dispensable for Sister-Chromatid Cohesion in Human Cells. Mol Biol Cell. Kato, A., Miyazaki, M., Ambiru, S., Yoshitomi, H., Ito, H., Nakagawa, K., Shimizu, H., Yokosuka, O., and Nakajima, N. (2001). Multidrug resistance gene (MDR-1) expression as a useful prognostic factor in patients with human hepatocellular carcinoma after surgical resection. J Surg Oncol 78, 110-115. Kim, E.H., Kim, S.U., Shin, D.Y., and Choi, K.S. (2004). Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP. Oncogene 23, 446-456. Kitajima, T.S., Hauf, S., Ohsugi, M., Yamamoto, T., and Watanabe, Y. (2005). Human Bub1 defines the persistent cohesion site along the mitotic chromosome by affecting Shugoshin localization. Curr Biol 15, 353-359. Kitajima, T.S., Sakuno, T., Ishiguro, K., Iemura, S., Natsume, T., Kawashima, S.A., and Watanabe, Y. (2006). Shugoshin collaborates with protein phosphatase 2A to protect cohesin. Nature 441, 46-52. Landry, J.J., Pyl, P.T., Rausch, T., Zichner, T., Tekkedil, M.M., Stutz, A.M., Jauch, A., Aiyar, R.S., Pau, G., Delhomme, N., et al. (2013). The genomic and transcriptomic landscape of a HeLa cell line. G3 (Bethesda) 3, 1213-1224. Lavanchy, D. (2005). Worldwide epidemiology of HBV infection, disease burden, and vaccine prevention. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 34 Suppl 1, S1-3. Lee, J., Kitajima, T.S., Tanno, Y., Yoshida, K., Morita, T., Miyano, T., Miyake, M., and Watanabe, Y. (2008). Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells. Nat Cell Biol 10, 42-52. Liu, D., Vader, G., Vromans, M.J., Lampson, M.A., and Lens, S.M. (2009). Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates. Science 323, 1350-1353. Liu, H., Jia, L., and Yu, H. (2013). Phospho-H2A and cohesin specify distinct tension-regulated Sgo1 pools at kinetochores and inner centromeres. Curr Biol 23, 1927-1933. Liu, H., Rankin, S., and Yu, H. (2012). Phosphorylation-enabled binding of SGO1-PP2A to cohesin protects sororin and centromeric cohesion during mitosis. Nat Cell Biol. Llovet, J.M., Ricci, S., Mazzaferro, V., Hilgard, P., Gane, E., Blanc, J.F., de Oliveira, A.C., Santoro, A., Raoul, J.L., Forner, A., et al. (2008). Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 359, 378-390. Locarnini, S. (2004). Molecular virology of hepatitis B virus. Seminars in liver disease 24 Suppl 1, 3-10. Longley, D.B., and Johnston, P.G. (2005). Molecular mechanisms of drug resistance. J Pathol 205, 275-292. Losada, A., Hirano, M., and Hirano, T. (1998). Identification of Xenopus SMC protein complexes required for sister chromatid cohesion. Genes Dev 12, 1986-1997. Losada, A., Hirano, M., and Hirano, T. (2002). Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis. Genes Dev 16, 3004-3016. MacCallum, D.E., Melville, J., Frame, S., Watt, K., Anderson, S., Gianella-Borradori, A., Lane, D.P., and Green, S.R. (2005). Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1. Cancer Res 65, 5399-5407. Matsuura, S., Kahyo, T., Shinmura, K., Iwaizumi, M., Yamada, H., Funai, K., Kobayashi, J., Tanahashi, M., Niwa, H., Ogawa, H., et al. (2013). SGOL1 variant B induces abnormal mitosis and resistance to taxane in non-small cell lung cancers. Sci Rep 3, 3012. McGuinness, B.E., Hirota, T., Kudo, N.R., Peters, J.M., and Nasmyth, K. (2005). Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells. PLoS Biol 3, e86. Meppelink, A., Kabeche, L., Vromans, M.J., Compton, D.A., and Lens, S.M. (2015). Shugoshin-1 balances Aurora B kinase activity via PP2A to promote chromosome bi-orientation. Cell Rep 11, 508-515. Morrow, C.J., Tighe, A., Johnson, V.L., Scott, M.I., Ditchfield, C., and Taylor, S.S. (2005). Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20. J Cell Sci 118, 3639-3652. Nakabayashi, H., Taketa, K., Miyano, K., Yamane, T., and Sato, J. (1982). Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. Cancer research 42, 3858-3863. Raghavan, P., Tumati, V., Yu, L., Chan, N., Tomimatsu, N., Burma, S., Bristow, R.G., and Saha, D. (2012). AZD5438, an inhibitor of Cdk1, 2, and 9, enhances the radiosensitivity of non-small cell lung carcinoma cells. Int J Radiat Oncol Biol Phys 84, e507-514. Reid, Y., Gaddipati, J.P., Yadav, D., and Kantor, J. (2009). Establishment of a human neonatal hepatocyte cell line. In Vitro Cell Dev Biol Anim 45, 535-542. Salic, A., Waters, J.C., and Mitchison, T.J. (2004). Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis. Cell 118, 567-578. Scanlan, M.J., and Jager, D. (2001). Challenges to the development of antigen-specific breast cancer vaccines. Breast cancer research : BCR 3, 95-98. Sudakin, V., Chan, G.K., and Yen, T.J. (2001). Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. J Cell Biol 154, 925-936. Sumara, I., Gimenez-Abian, J.F., Gerlich, D., Hirota, T., Kraft, C., de la Torre, C., Ellenberg, J., and Peters, J.M. (2004). Roles of polo-like kinase 1 in the assembly of functional mitotic spindles. Curr Biol 14, 1712-1722. Sumara, I., Vorlaufer, E., Stukenberg, P.T., Kelm, O., Redemann, N., Nigg, E.A., and Peters, J.M. (2002). The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Mol Cell 9, 515-525. Tai, W.T., Cheng, A.L., Shiau, C.W., Liu, C.Y., Ko, C.H., Lin, M.W., Chen, P.J., and Chen, K.F. (2012). Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3. Mol Cancer Ther 11, 452-463. Tanaka, T., Fuchs, J., Loidl, J., and Nasmyth, K. (2000). Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation. Nat Cell Biol 2, 492-499. Tang, Z., Bharadwaj, R., Li, B., and Yu, H. (2001). Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1. Dev Cell 1, 227-237. Tang, Z., Shu, H., Qi, W., Mahmood, N.A., Mumby, M.C., and Yu, H. (2006). PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation. Dev Cell 10, 575-585. Thornton, B.R., and Toczyski, D.P. (2003). Securin and B-cyclin/CDK are the only essential targets of the APC. Nat Cell Biol 5, 1090-1094. Torre, L.A., Bray, F., Siegel, R.L., Ferlay, J., Lortet-Tieulent, J., and Jemal, A. (2015). Global Cancer Statistics, 2012. Ca-Cancer J Clin 65, 87-108. van Malenstein, H., Dekervel, J., Verslype, C., Van Cutsem, E., Windmolders, P., Nevens, F., and van Pelt, J. (2013). Long-term exposure to sorafenib of liver cancer cells induces resistance with epithelial-to-mesenchymal transition, increased invasion and risk of rebound growth. Cancer Lett 329, 74-83. Waizenegger, I.C., Hauf, S., Meinke, A., and Peters, J.M. (2000). Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase. Cell 103, 399-410. Walsby, E., Lazenby, M., Pepper, C., and Burnett, A.K. (2011). The cyclin-dependent kinase inhibitor SNS-032 has single agent activity in AML cells and is highly synergistic with cytarabine. Leukemia 25, 411-419. Wang, H.C., Chang, W.T., Chang, W.W., Wu, H.C., Huang, W., Lei, H.Y., Lai, M.D., Fausto, N., and Su, I.J. (2005). Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes. Hepatology 41, 761-770. Wang, L.H., Yen, C.J., Li, T.N., Elowe, S., Wang, W.C., and Wang, L.H. (2015). Sgo1 is a potential therapeutic target for hepatocellular carcinoma. Oncotarget 6, 2023-2033. Wang, X., Yang, Y., and Dai, W. (2006). Differential subcellular localizations of two human Sgo1 isoforms: implications in regulation of sister chromatid cohesion and microtubule dynamics. Cell Cycle 5, 635-640. Wang, X., Yang, Y., Duan, Q., Jiang, N., Huang, Y., Darzynkiewicz, Z., and Dai, W. (2008). sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1. Dev Cell 14, 331-341. Woodhouse, J.R., and Ferry, D.R. (1995). The genetic basis of resistance to cancer chemotherapy. Annals of medicine 27, 157-167. Wu, H.C., Tsai, H.W., Teng, C.F., Hsieh, W.C., Lin, Y.J., Wang, L.H., Yuan, Q., and Su, I.J. (2014). Ground-glass hepatocytes co-expressing hepatitis B virus X protein and surface antigens exhibit enhanced oncogenic effects and tumorigenesis. Hum Pathol 45, 1294-1301. Xie, G., Tang, H., Wu, S., Chen, J., Liu, J., and Liao, C. (2014). The cyclin-dependent kinase inhibitor SNS-032 induces apoptosis in breast cancer cells via depletion of Mcl-1 and X-linked inhibitor of apoptosis protein and displays antitumor activity in vivo. Int J Oncol 45, 804-812. Xu, Z., Cetin, B., Anger, M., Cho, U.S., Helmhart, W., Nasmyth, K., and Xu, W. (2009). Structure and function of the PP2A-shugoshin interaction. Mol Cell 35, 426-441. Yamada, H.Y., Yao, Y., Wang, X., Zhang, Y., Huang, Y., Dai, W., and Rao, C.V. (2012). Haploinsufficiency of SGO1 results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis. Cell Cycle 11, 479-488. Yang, J., Ikezoe, T., Nishioka, C., and Yokoyama, A. (2012). A novel treatment strategy targeting shugoshin 1 in hematological malignancies. Leuk Res. Yuen, K.W.Y. (2001). Chromosome Instability (CIN), Aneuploidy and Cancer. In eLS (John Wiley & Sons, Ltd). Zhu, A.X. (2006). Systemic therapy of advanced hepatocellular carcinoma: how hopeful should we be? Oncologist 11, 790-800. Matsuura, S., Kahyo, T., Shinmura, K., Iwaizumi, M., Yamada, H., Funai, K., Kobayashi, J., Tanahashi, M., Niwa, H., Ogawa, H., et al. (2013). SGOL1 variant B induces abnormal mitosis and resistance to taxane in non-small cell lung cancers. Sci Rep 3, 3012. McGuinness, B.E., Hirota, T., Kudo, N.R., Peters, J.M., and Nasmyth, K. (2005). Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells. PLoS Biol 3, e86. Meppelink, A., Kabeche, L., Vromans, M.J., Compton, D.A., and Lens, S.M. (2015). Shugoshin-1 balances Aurora B kinase activity via PP2A to promote chromosome bi-orientation. Cell Rep 11, 508-515. Morrow, C.J., Tighe, A., Johnson, V.L., Scott, M.I., Ditchfield, C., and Taylor, S.S. (2005). Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20. J Cell Sci 118, 3639-3652. Nakabayashi, H., Taketa, K., Miyano, K., Yamane, T., and Sato, J. (1982). Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. Cancer research 42, 3858-3863. Raghavan, P., Tumati, V., Yu, L., Chan, N., Tomimatsu, N., Burma, S., Bristow, R.G., and Saha, D. (2012). AZD5438, an inhibitor of Cdk1, 2, and 9, enhances the radiosensitivity of non-small cell lung carcinoma cells. Int J Radiat Oncol Biol Phys 84, e507-514. Reid, Y., Gaddipati, J.P., Yadav, D., and Kantor, J. (2009). Establishment of a human neonatal hepatocyte cell line. In Vitro Cell Dev Biol Anim 45, 535-542. Salic, A., Waters, J.C., and Mitchison, T.J. (2004). Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosis. Cell 118, 567-578. Scanlan, M.J., and Jager, D. (2001). Challenges to the development of antigen-specific breast cancer vaccines. Breast cancer research : BCR 3, 95-98. Sudakin, V., Chan, G.K., and Yen, T.J. (2001). Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2. J Cell Biol 154, 925-936. Sumara, I., Gimenez-Abian, J.F., Gerlich, D., Hirota, T., Kraft, C., de la Torre, C., Ellenberg, J., and Peters, J.M. (2004). Roles of polo-like kinase 1 in the assembly of functional mitotic spindles. Curr Biol 14, 1712-1722. Sumara, I., Vorlaufer, E., Stukenberg, P.T., Kelm, O., Redemann, N., Nigg, E.A., and Peters, J.M. (2002). The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase. Mol Cell 9, 515-525. Tai, W.T., Cheng, A.L., Shiau, C.W., Liu, C.Y., Ko, C.H., Lin, M.W., Chen, P.J., and Chen, K.F. (2012). Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3. Mol Cancer Ther 11, 452-463. Tanaka, T., Fuchs, J., Loidl, J., and Nasmyth, K. (2000). Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation. Nat Cell Biol 2, 492-499. Tang, Z., Bharadwaj, R., Li, B., and Yu, H. (2001). Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1. Dev Cell 1, 227-237. Tang, Z., Shu, H., Qi, W., Mahmood, N.A., Mumby, M.C., and Yu, H. (2006). PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation. Dev Cell 10, 575-585. Thornton, B.R., and Toczyski, D.P. (2003). Securin and B-cyclin/CDK are the only essential targets of the APC. Nat Cell Biol 5, 1090-1094. Torre, L.A., Bray, F., Siegel, R.L., Ferlay, J., Lortet-Tieulent, J., and Jemal, A. (2015). Global Cancer Statistics, 2012. Ca-Cancer J Clin 65, 87-108. van Malenstein, H., Dekervel, J., Verslype, C., Van Cutsem, E., Windmolders, P., Nevens, F., and van Pelt, J. (2013). Long-term exposure to sorafenib of liver cancer cells induces resistance with epithelial-to-mesenchymal transition, increased invasion and risk of rebound growth. Cancer Lett 329, 74-83. Waizenegger, I.C., Hauf, S., Meinke, A., and Peters, J.M. (2000). Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase. Cell 103, 399-410. Walsby, E., Lazenby, M., Pepper, C., and Burnett, A.K. (2011). The cyclin-dependent kinase inhibitor SNS-032 has single agent activity in AML cells and is highly synergistic with cytarabine. Leukemia 25, 411-419. Wang, H.C., Chang, W.T., Chang, W.W., Wu, H.C., Huang, W., Lei, H.Y., Lai, M.D., Fausto, N., and Su, I.J. (2005). Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes. Hepatology 41, 761-770. Wang, X., Yang, Y., and Dai, W. (2006). Differential subcellular localizations of two human Sgo1 isoforms: implications in regulation of sister chromatid cohesion and microtubule dynamics. Cell Cycle 5, 635-640. Wang, X., Yang, Y., Duan, Q., Jiang, N., Huang, Y., Darzynkiewicz, Z., and Dai, W. (2008). sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1. Dev Cell 14, 331-341. Woodhouse, J.R., and Ferry, D.R. (1995). The genetic basis of resistance to cancer chemotherapy. Annals of medicine 27, 157-167. Wu, H.C., Tsai, H.W., Teng, C.F., Hsieh, W.C., Lin, Y.J., Wang, L.H., Yuan, Q., and Su, I.J. (2014). Ground-glass hepatocytes co-expressing hepatitis B virus X protein and surface antigens exhibit enhanced oncogenic effects and tumorigenesis. Hum Pathol 45, 1294-1301. Xie, G., Tang, H., Wu, S., Chen, J., Liu, J., and Liao, C. (2014). The cyclin-dependent kinase inhibitor SNS-032 induces apoptosis in breast cancer cells via depletion of Mcl-1 and X-linked inhibitor of apoptosis protein and displays antitumor activity in vivo. Int J Oncol 45, 804-812. Xu, Z., Cetin, B., Anger, M., Cho, U.S., Helmhart, W., Nasmyth, K., and Xu, W. (2009). Structure and function of the PP2A-shugoshin interaction. Mol Cell 35, 426-441. Yamada, H.Y., Yao, Y., Wang, X., Zhang, Y., Huang, Y., Dai, W., and Rao, C.V. (2012). Haploinsufficiency of SGO1 results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis. Cell Cycle 11, 479-488. Yang, J., Ikezoe, T., Nishioka, C., and Yokoyama, A. (2012). A novel treatment strategy targeting shugoshin 1 in hematological malignancies. Leuk Res. Yuen, K.W.Y. (2001). Chromosome Instability (CIN), Aneuploidy and Cancer. In eLS (John Wiley & Sons, Ltd). Zhu, A.X. (2006). Systemic therapy of advanced hepatocellular carcinoma: how hopeful should we be? Oncologist 11, 790-800.
|