|
1. Rothenberg ME, Hogan SP: The eosinophil. Annual review of immunology 2006, 24:147-174. 2. McEwen BJ: Eosinophils: a review. Veterinary research communications 1992, 16(1):11-44. 3. Gleich GJ, Loegering DA: Immunobiology of eosinophils. Annual review of immunology 1984, 2:429-459. 4. Weller PF: Eosinophils: structure and functions. Current opinion in immunology 1994, 6(1):85-90. 5. Venge P, Bystrom J, Carlson M, Hakansson L, Karawacjzyk M, Peterson C, Seveus L, Trulson A: Eosinophil cationic protein (ECP): molecular and biological properties and the use of ECP as a marker of eosinophil activation in disease. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1999, 29(9):1172-1186. 6. Stenfeldt AL, Wenneras C: Danger signals derived from stressed and necrotic epithelial cells activate human eosinophils. Immunology 2004, 112(4):605-614. 7. Gleich GJ, Adolphson CR: The eosinophilic leukocyte: structure and function. Advances in immunology 1986, 39:177-253. 8. Molina HA, Kierszenbaum F, Hamann KJ, Gleich GJ: Toxic effects produced or mediated by human eosinophil granule components on Trypanosoma cruzi. The American journal of tropical medicine and hygiene 1988, 38(2):327-334. 9. Carreras E, Boix E, Navarro S, Rosenberg HF, Cuchillo CM, Nogues MV: Surface-exposed amino acids of eosinophil cationic protein play a critical role in the inhibition of mammalian cell proliferation. Mol Cell Biochem 2005, 272(1-2):1-7. 10. Motojima S, Frigas E, Loegering DA, Gleich GJ: Toxicity of eosinophil cationic proteins for guinea pig tracheal epithelium in vitro. Am Rev Respir Dis 1989, 139(3):801-805. 11. Ali S, Kaur J, Patel KD: Intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1, and regulated on activation normal T cell expressed and secreted are expressed by human breast carcinoma cells and support eosinophil adhesion and activation. Am J Pathol 2000, 157(1):313-321. 12. Lehrer RI, Szklarek D, Barton A, Ganz T, Hamann KJ, Gleich GJ: Antibacterial properties of eosinophil major basic protein and eosinophil cationic protein. Journal of immunology (Baltimore, Md : 1950) 1989, 142(12):4428-4434. 13. Domachowske JB, Dyer KD, Adams AG, Leto TL, Rosenberg HF: Eosinophil cationic protein/RNase 3 is another RNase A-family ribonuclease with direct antiviral activity. Nucleic acids research 1998, 26(14):3358-3363. 14. Torrent M, Cuyas E, Carreras E, Navarro S, Lopez O, de la Maza A, Nogues MV, Reshetnyak YK, Boix E: Topography studies on the membrane interaction mechanism of the eosinophil cationic protein. Biochemistry 2007, 46(3):720-733. 15. Young JD, Peterson CG, Venge P, Cohn ZA: Mechanism of membrane damage mediated by human eosinophil cationic protein. Nature 1986, 321(6070):613-616. 16. Peterson CG, Jornvall H, Venge P: Purification and characterization of eosinophil cationic protein from normal human eosinophils. European journal of haematology 1988, 40(5):415-423. 17. Malabanan AO, Turner AK, Rosenberg IN, Holick MF: Oncogenic osteomalacia: clinical presentation, densitometric findings, and response to therapy. Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry 1998, 1(1):77-80. 18. Rosenberg HF, Ackerman SJ, Tenen DG: Human eosinophil cationic protein. Molecular cloning of a cytotoxin and helminthotoxin with ribonuclease activity. J Exp Med 1989, 170(1):163-176. 19. Mallorqui-Fernandez G, Pous J, Peracaula R, Aymami J, Maeda T, Tada H, Yamada H, Seno M, de Llorens R, Gomis-Ruth FX et al: Three-dimensional crystal structure of human eosinophil cationic protein (RNase 3) at 1.75 A resolution. Journal of molecular biology 2000, 300(5):1297-1307. 20. Rosenberg HF: Recombinant human eosinophil cationic protein. Ribonuclease activity is not essential for cytotoxicity. The Journal of biological chemistry 1995, 270(14):7876-7881. 21. Makarov AA, Ilinskaya ON: Cytotoxic ribonucleases: molecular weapons and their targets. FEBS letters 2003, 540(1-3):15-20. 22. Maeda T, Kitazoe M, Tada H, de Llorens R, Salomon DS, Ueda M, Yamada H, Seno M: Growth inhibition of mammalian cells by eosinophil cationic protein. European journal of biochemistry / FEBS 2002, 269(1):307-316. 23. Gleich GJ, Loegering DA, Bell MP, Checkel JL, Ackerman SJ, McKean DJ: Biochemical and functional similarities between human eosinophil-derived neurotoxin and eosinophil cationic protein: homology with ribonuclease. Proceedings of the National Academy of Sciences of the United States of America 1986, 83(10):3146-3150. 24. Fan TC, Chang HT, Chen IW, Wang HY, Chang MD: A heparan sulfate-facilitated and raft-dependent macropinocytosis of eosinophil cationic protein. Traffic 2007, 8(12):1778-1795. 25. Fang SL, Fan TC, Fu HW, Chen CJ, Hwang CS, Hung TJ, Lin LY, Chang MD: A novel cell-penetrating peptide derived from human eosinophil cationic protein. PLoS One 2013, 8(3):e57318. 26. Fan TC, Fang SL, Hwang CS, Hsu CY, Lu XA, Hung SC, Lin SC, Chang MD: Characterization of molecular interactions between eosinophil cationic protein and heparin. J Biol Chem 2008, 283(37):25468-25474. 27. Lien PC, Kuo PH, Chen CJ, Chang HH, Fang SL, Wu WS, Lai YK, Pai TW, Chang MD: In silico prediction and in vitro characterization of multifunctional human RNase3. Biomed Res Int 2013, 2013:170398. 28. Chen C-J, Tsai K-C, Kuo P-H, Chang P-L, Wang W-C, Chuang Y-J, Chang MD-T: A Heparan Sulfate-Binding Cell Penetrating Peptide for Tumor Targeting and Migration Inhibition. BioMed Research International. 29. Prydz K, Dalen KT: Synthesis and sorting of proteoglycans. Journal of cell science 2000, 113 Pt 2:193-205. 30. Gandhi NS, Mancera RL: The structure of glycosaminoglycans and their interactions with proteins. Chemical biology & drug design 2008, 72(6):455-482. 31. Abes R, Arzumanov AA, Moulton HM, Abes S, Ivanova GD, Iversen PL, Gait MJ, Lebleu B: Cell-penetrating-peptide-based delivery of oligonucleotides: an overview. Biochemical Society transactions 2007, 35(Pt 4):775-779. 32. Knelson EH, Nee JC, Blobe GC: Heparan sulfate signaling in cancer. Trends in biochemical sciences 2014, 39(6):277-288. 33. Fernandez-Vega I, Garcia O, Crespo A, Castanon S, Menendez P, Astudillo A, Quiros LM: Specific genes involved in synthesis and editing of heparan sulfate proteoglycans show altered expression patterns in breast cancer. BMC Cancer 2013, 13:24. 34. Sarrazin S, Lamanna WC, Esko JD: Heparan sulfate proteoglycans. Cold Spring Harb Perspect Biol 2011, 3(7). 35. Theocharis AD, Skandalis SS, Tzanakakis GN, Karamanos NK: Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting. The FEBS journal 2010, 277(19):3904-3923. 36. Hirabayashi K, Numa F, Suminami Y, Murakami A, Murakami T, Kato H: Altered proliferative and metastatic potential associated with increased expression of syndecan-1. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 1998, 19(6):454-463. 37. Partovian C, Ju R, Zhuang ZW, Martin KA, Simons M: Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells. Mol Cell 2008, 32(1):140-149. 38. Bass MD, Roach KA, Morgan MR, Mostafavi-Pour Z, Schoen T, Muramatsu T, Mayer U, Ballestrem C, Spatz JP, Humphries MJ: Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix. J Cell Biol 2007, 177(3):527-538. 39. Park H, Kim Y, Lim Y, Han I, Oh ES: Syndecan-2 mediates adhesion and proliferation of colon carcinoma cells. J Biol Chem 2002, 277(33):29730-29736. 40. Muramatsu T, Saitoh M, Ro Y, Uekusa T, Iwamura E, Ohta K, Kohno Y, Abiko Y, Shimono M: Inhibition of syndecan-1 expression and function in oral cancer cells. Oncol Rep 2008, 20(6):1353-1357. 41. Pacifici M, Shimo T, Gentili C, Kirsch T, Freeman TA, Enomoto-Iwamoto M, Iwamoto M, Koyama E: Syndecan-3: a cell-surface heparan sulfate proteoglycan important for chondrocyte proliferation and function during limb skeletogenesis. J Bone Miner Metab 2005, 23(3):191-199. 42. Carvallo L, Munoz R, Bustos F, Escobedo N, Carrasco H, Olivares G, Larrain J: Non-canonical Wnt signaling induces ubiquitination and degradation of Syndecan4. J Biol Chem 2010, 285(38):29546-29555. 43. Matsuda K, Maruyama H, Guo F, Kleeff J, Itakura J, Matsumoto Y, Lander AD, Korc M: Glypican-1 is overexpressed in human breast cancer and modulates the mitogenic effects of multiple heparin-binding growth factors in breast cancer cells. Cancer research 2001, 61(14):5562-5569. 44. Kurosawa N, Chen GY, Kadomatsu K, Ikematsu S, Sakuma S, Muramatsu T: Glypican-2 binds to midkine: the role of glypican-2 in neuronal cell adhesion and neurite outgrowth. Glycoconj J 2001, 18(6):499-507. 45. Liu B, Bell AW, Paranjpe S, Bowen WC, Khillan JS, Luo JH, Mars WM, Michalopoulos GK: Suppression of liver regeneration and hepatocyte proliferation in hepatocyte-targeted glypican 3 transgenic mice. Hepatology 2010, 52(3):1060-1067. 46. Strate I, Tessadori F, Bakkers J: Glypican4 promotes cardiac specification and differentiation by attenuating canonical Wnt and Bmp signaling. Development 2015, 142(10):1767-1776. 47. Li Y, Miao L, Cai H, Ding J, Xiao Y, Yang J, Zhang D: The overexpression of glypican-5 promotes cancer cell migration and is associated with shorter overall survival in non-small cell lung cancer. Oncology letters 2013, 6(6):1565-1572. 48. Kawahara R, Granato DC, Carnielli CM, Cervigne NK, Oliveria CE, Martinez CA, Yokoo S, Fonseca FP, Lopes M, Santos-Silva AR et al: Agrin and perlecan mediate tumorigenic processes in oral squamous cell carcinoma. PLoS One 2014, 9(12):e115004. 49. Salmivirta M, Safaiyan F, Prydz K, Andresen MS, Aryan M, Kolset SO: Differentiation-associated modulation of heparan sulfate structure and function in CaCo-2 colon carcinoma cells. Glycobiology 1998, 8(10):1029-1036. 50. Horai T, Nakamura N, Tateishi R, Hattori S: Glycosaminoglycans in human lung cancer. Cancer 1981, 48(9):2016-2021. 51. Masuda H, Ozeki T, Takazono I, Tanaka Y: Analyses of glycosaminoglycans in human lung cancer. Biochemical medicine and metabolic biology 1987, 37(3):366-373. 52. Grigoriu BD, Depontieu F, Scherpereel A, Gourcerol D, Devos P, Ouatas T, Lafitte JJ, Copin MC, Tonnel AB, Lassalle P: Endocan expression and relationship with survival in human non-small cell lung cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 2006, 12(15):4575-4582. 53. Raman K, Kuberan B: Chemical Tumor Biology of Heparan Sulfate Proteoglycans. Current chemical biology 2010, 4(1):20-31. 54. Zuo L, Zhang SM, Hu RL, Zhu HQ, Zhou Q, Gui SY, Wu Q, Wang Y: Correlation between expression and differentiation of endocan in colorectal cancer. World journal of gastroenterology : WJG 2008, 14(28):4562-4568. 55. Asimakopoulou AP, Theocharis AD, Tzanakakis GN, Karamanos NK: The biological role of chondroitin sulfate in cancer and chondroitin-based anticancer agents. In vivo 2008, 22(3):385-389. 56. Yip GW, Smollich M, Gotte M: Therapeutic value of glycosaminoglycans in cancer. Molecular cancer therapeutics 2006, 5(9):2139-2148. 57. Adany R, Heimer R, Caterson B, Sorrell JM, Iozzo RV: Altered expression of chondroitin sulfate proteoglycan in the stroma of human colon carcinoma. Hypomethylation of PG-40 gene correlates with increased PG-40 content and mRNA levels. The Journal of biological chemistry 1990, 265(19):11389-11396. 58. Gatza CE, Holtzhausen A, Kirkbride KC, Morton A, Gatza ML, Datto MB, Blobe GC: Type III TGF-beta receptor enhances colon cancer cell migration and anchorage-independent growth. Neoplasia 2011, 13(8):758-770. 59. Cooney CA, Jousheghany F, Yao-Borengasser A, Phanavanh B, Gomes T, Kieber-Emmons AM, Siegel ER, Suva LJ, Ferrone S, Kieber-Emmons T et al: Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11 gene expression in forming surface P-selectin ligands in aggressive breast cancer cells. Breast cancer research : BCR 2011, 13(3):R58. 60. Vijayagopal P, Figueroa JE, Levine EA: Altered composition and increased endothelial cell proliferative activity of proteoglycans isolated from breast carcinoma. Journal of surgical oncology 1998, 68(4):250-254. 61. Fujii M, Yusa A, Yokoyama Y, Kokuryo T, Tsunoda N, Oda K, Nagino M, Ishimaru T, Shimoyama Y, Utsunomiya H et al: Cytoplasmic expression of the JM403 antigen GlcA-GlcNH3+ on heparan sulfate glycosaminoglycan in mammary carcinomas--a novel proliferative biomarker for breast cancers with high malignancy. Glycoconjugate journal 2010, 27(7-9):661-672. 62. De Klerk DP, Lee DV, Human HJ: Glycosaminoglycans of human prostatic cancer. J Urol 1984, 131(5):1008-1012. 63. Theocharis AD, Vynios DH, Papageorgakopoulou N, Skandalis SS, Theocharis DA: Altered content composition and structure of glycosaminoglycans and proteoglycans in gastric carcinoma. Int J Biochem Cell Biol 2003, 35(3):376-390. 64. Hishinuma M, Ohashi KI, Yamauchi N, Kashima T, Uozaki H, Ota S, Kodama T, Aburatani H, Fukayama M: Hepatocellular oncofetal protein, glypican 3 is a sensitive marker for alpha-fetoprotein-producing gastric carcinoma. Histopathology 2006, 49(5):479-486. 65. Masuda H, Ozeki T, Takazono I, Tanaka Y: Composition of glycosaminoglycans in human pancreatic cancer. Biochem Med Metab Biol 1989, 41(3):193-200. 66. Hrabar D, Aralica G, Gomercic M, Ljubicic N, Kruslin B, Tomas D: Epithelial and stromal expression of syndecan-2 in pancreatic carcinoma. Anticancer Res, 30(7):2749-2753. 67. Kleeff J, Ishiwata T, Kumbasar A, Friess H, Buchler MW, Lander AD, Korc M: The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer. The Journal of clinical investigation 1998, 102(9):1662-1673. 68. Yang Y, Macleod V, Dai Y, Khotskaya-Sample Y, Shriver Z, Venkataraman G, Sasisekharan R, Naggi A, Torri G, Casu B et al: The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy. Blood 2007, 110(6):2041-2048. 69. Kalluri R, Weinberg RA: The basics of epithelial-mesenchymal transition. The Journal of clinical investigation 2009, 119(6):1420-1428. 70. Mirandola L, Figueroa JA, Phan TT, Grizzi F, Kim M, Rahman RL, Jenkins MR, Cobos E, Jumper C, Alalawi R et al: Novel antigens in non-small cell lung cancer: SP17, AKAP4, and PTTG1 are potential immunotherapeutic targets. Oncotarget 2015, 6(5):2812-2826. 71. Margaretten NC, Witschi HR: Effects of hyperoxia on growth of experimental lung metastasis. Carcinogenesis 1988, 9(3):433-439. 72. Prokop A, Davidson JM: Nanovehicular intracellular delivery systems. J Pharm Sci 2008, 97(9):3518-3590. 73. Akram S, Mirza T, Aamir Mirza M, Qureshi M: Emerging Patterns in Clinico-pathological spectrum of Oral Cancers. Pak J Med Sci 2013, 29(3):783-787. 74. Chen IC, Chiang WF, Huang HH, Chen PF, Shen YY, Chiang HC: Role of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis. Mol Cancer 2014, 13:254. 75. Liu SA, Tsai WC, Wong YK, Lin JC, Poon CK, Chao SY, Hsiao YL, Chan MY, Cheng CS, Wang CC et al: Nutritional factors and survival of patients with oral cancer. Head Neck 2006, 28(11):998-1007. 76. Lin WJ, Jiang RS, Wu SH, Chen FJ, Liu SA: Smoking, alcohol, and betel quid and oral cancer: a prospective cohort study. J Oncol 2011, 2011:525976. 77. Ramadas K, Sankaranarayanan R, Jacob BJ, Thomas G, Somanathan T, Mahe C, Pandey M, Abraham E, Najeeb S, Mathew B et al: Interim results from a cluster randomized controlled oral cancer screening trial in Kerala, India. Oral Oncol 2003, 39(6):580-588. 78. Khusial PR, Vadla B, Krishnan H, Ramlall TF, Shen Y, Ichikawa H, Geng JG, Goldberg GS: Src activates Abl to augment Robo1 expression in order to promote tumor cell migration. Oncotarget 2010, 1(3):198-209. 79. Tang S, Morgan KG, Parker C, Ware JA: Requirement for protein kinase C theta for cell cycle progression and formation of actin stress fibers and filopodia in vascular endothelial cells. The Journal of biological chemistry 1997, 272(45):28704-28711. 80. Chambers AF, Groom AC, MacDonald IC: Dissemination and growth of cancer cells in metastatic sites. Nature reviews Cancer 2002, 2(8):563-572. 81. Mook OR, Frederiks WM, Van Noorden CJ: The role of gelatinases in colorectal cancer progression and metastasis. Biochimica et biophysica acta 2004, 1705(2):69-89. 82. Ma L, Weinberg RA: Micromanagers of malignancy: role of microRNAs in regulating metastasis. Trends Genet 2008, 24(9):448-456. 83. Kim SJ, Park JW, Yoon JS, Mok JO, Kim YJ, Park HK, Kim CH, Byun DW, Lee YJ, Jin SY et al: Increased expression of focal adhesion kinase in thyroid cancer: immunohistochemical study. J Korean Med Sci 2004, 19(5):710-715. 84. Sen B, Johnson FM: Regulation of SRC family kinases in human cancers. J Signal Transduct 2011, 2011:865819. 85. Barkan D, El Touny LH, Michalowski AM, Smith JA, Chu I, Davis AS, Webster JD, Hoover S, Simpson RM, Gauldie J et al: Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment. Cancer Res 2010, 70(14):5706-5716. 86. Mayer EL, Krop IE: Advances in targeting SRC in the treatment of breast cancer and other solid malignancies. Clin Cancer Res 2010, 16(14):3526-3532. 87. Carelli S, Zadra G, Vaira V, Falleni M, Bottiglieri L, Nosotti M, Di Giulio AM, Gorio A, Bosari S: Up-regulation of focal adhesion kinase in non-small cell lung cancer. Lung Cancer 2006, 53(3):263-271. 88. Summy JM, Gallick GE: Treatment for advanced tumors: SRC reclaims center stage. Clin Cancer Res 2006, 12(5):1398-1401. 89. Lee TY, Folkman J, Javaherian K: HSPG-binding peptide corresponding to the exon 6a-encoded domain of VEGF inhibits tumor growth by blocking angiogenesis in murine model. PloS one 2010, 5(4):e9945. 90. Hibino S, Shibuya M, Hoffman MP, Engbring JA, Hossain R, Mochizuki M, Kudoh S, Nomizu M, Kleinman HK: Laminin alpha5 chain metastasis- and angiogenesis-inhibiting peptide blocks fibroblast growth factor 2 activity by binding to the heparan sulfate chains of CD44. Cancer research 2005, 65(22):10494-10501. 91. Hibino S, Shibuya M, Engbring JA, Mochizuki M, Nomizu M, Kleinman HK: Identification of an active site on the laminin alpha5 chain globular domain that binds to CD44 and inhibits malignancy. Cancer research 2004, 64(14):4810-4816. 92. Zhang L, Parry GC, Levin EG: Inhibition of tumor cell migration by LD22-4, an N-terminal fragment of 24-kDa FGF2, is mediated by Neuropilin 1. Cancer research 2013, 73(11):3316-3325. 93. Sulochana KN, Fan H, Jois S, Subramanian V, Sun F, Kini RM, Ge R: Peptides derived from human decorin leucine-rich repeat 5 inhibit angiogenesis. J Biol Chem 2005, 280(30):27935-27948. 94. Pietraszek K, Brezillon S, Perreau C, Malicka-Blaszkiewicz M, Maquart FX, Wegrowski Y: Lumican - derived peptides inhibit melanoma cell growth and migration. PLoS One 2013, 8(10):e76232. 95. Mehta RR, Yamada T, Taylor BN, Christov K, King ML, Majumdar D, Lekmine F, Tiruppathi C, Shilkaitis A, Bratescu L et al: A cell penetrating peptide derived from azurin inhibits angiogenesis and tumor growth by inhibiting phosphorylation of VEGFR-2, FAK and Akt. Angiogenesis 2011, 14(3):355-369. 96. Michod D, Yang JY, Chen J, Bonny C, Widmann C: A RasGAP-derived cell permeable peptide potently enhances genotoxin-induced cytotoxicity in tumor cells. Oncogene 2004, 23(55):8971-8978. 97. Barras D, Lorusso G, Ruegg C, Widmann C: Inhibition of cell migration and invasion mediated by the TAT-RasGAP317-326 peptide requires the DLC1 tumor suppressor. Oncogene 2014, 33(44):5163-5172. 98. Zvaifler NJ: Relevance of the stroma and epithelial-mesenchymal transition (EMT) for the rheumatic diseases. Arthritis Res Ther 2006, 8(3):210. 99. Kang Y, Massague J: Epithelial-mesenchymal transitions: twist in development and metastasis. Cell 2004, 118(3):277-279. 100. Xie D, Gore C, Liu J, Pong RC, Mason R, Hao G, Long M, Kabbani W, Yu L, Zhang H et al: Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis. Proc Natl Acad Sci U S A 2010, 107(6):2485-2490. 101. Thiery JP, Acloque H, Huang RY, Nieto MA: Epithelial-mesenchymal transitions in development and disease. Cell 2009, 139(5):871-890. 102. Peinado H, Olmeda D, Cano A: Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 2007, 7(6):415-428. 103. Fenouille N, Tichet M, Dufies M, Pottier A, Mogha A, Soo JK, Rocchi S, Mallavialle A, Galibert MD, Khammari A et al: The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion. PLoS One 2012, 7(7):e40378. 104. O'Brien J, Wilson I, Orton T, Pognan F: Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. European journal of biochemistry / FEBS 2000, 267(17):5421-5426. 105. Holmes E, Engvall E: Determination of integrins on cells by cell adhesion to antibodies. Anal Biochem 1993, 214(1):100-105. 106. Gomes AM, Stelling MP, Pavao MS: Heparan sulfate and heparanase as modulators of breast cancer progression. Biomed Res Int 2013, 2013:852093. 107. van Zijl F, Krupitza G, Mikulits W: Initial steps of metastasis: cell invasion and endothelial transmigration. Mutat Res 2011, 728(1-2):23-34. 108. Park GB, Kim DJ, Kim YS, Lee HK, Kim CW, Hur DY: Silencing of galectin-3 represses osteosarcoma cell migration and invasion through inhibition of FAK/Src/Lyn activation and beta-catenin expression and increases susceptibility to chemotherapeutic agents. Int J Oncol 2015, 46(1):185-194. 109. Chen J, Li Z, Zhang S, Zhang R, Dassarath M, Wu G: Effects of exogenous VEGF(165)b on invasion and migration of human lung adenocarcinoma A549 cells. J Huazhong Univ Sci Technolog Med Sci 2011, 31(5):619-624. 110. Jouve N, Bachelier R, Despoix N, Blin MG, Matinzadeh MK, Poitevin S, Aurrand-Lions M, Fallague K, Bardin N, Blot-Chabaud M et al: CD146 mediates VEGF-induced melanoma cell extravasation through FAK activation. Int J Cancer 2015, 137(1):50-60. 111. Laird AD, Li G, Moss KG, Blake RA, Broome MA, Cherrington JM, Mendel DB: Src family kinase activity is required for signal tranducer and activator of transcription 3 and focal adhesion kinase phosphorylation and vascular endothelial growth factor signaling in vivo and for anchorage-dependent and -independent growth of human tumor cells. Mol Cancer Ther 2003, 2(5):461-469. 112. Nieto MA: Epithelial-Mesenchymal Transitions in development and disease: old views and new perspectives. Int J Dev Biol 2009, 53(8-10):1541-1547. 113. Zavadil J, Bottinger EP: TGF-beta and epithelial-to-mesenchymal transitions. Oncogene 2005, 24(37):5764-5774. 114. Satelli A, Li S: Vimentin in cancer and its potential as a molecular target for cancer therapy. Cell Mol Life Sci 2011, 68(18):3033-3046. 115. Sameni M, Dosescu J, Yamada KM, Sloane BF, Cavallo-Medved D: Functional live-cell imaging demonstrates that beta1-integrin promotes type IV collagen degradation by breast and prostate cancer cells. Mol Imaging 2008, 7(5):199-213. 116. Guo L, Zhang F, Cai Y, Liu T: Expression profiling of integrins in lung cancer cells. Pathol Res Pract 2009, 205(12):847-853. 117. Lin SC, Liu CJ, Chiu CP, Chang SM, Lu SY, Chen YJ: Establishment of OC3 oral carcinoma cell line and identification of NF-kappa B activation responses to areca nut extract. J Oral Pathol Med 2004, 33(2):79-86. 118. Kok SH, Hong CY, Lin SK, Lee JJ, Chiang CP, Kuo MY: Establishment and characterization of a tumorigenic cell line from areca quid and tobacco smoke-associated buccal carcinoma. Oral Oncol 2007, 43(7):639-647. 119. Tu HP, Fu E, Chen YT, Wu MH, Cheng LC, Yang SF: Expression of p21 and p53 in rat gingival and human oral epithelial cells after cyclosporine A treatment. J Periodontal Res 2008, 43(1):32-39. 120. Rheinwald JG, Beckett MA: Defective terminal differentiation in culture as a consistent and selectable character of malignant human keratinocytes. Cell 1980, 22(2 Pt 2):629-632. 121. Afratis N, Gialeli C, Nikitovic D, Tsegenidis T, Karousou E, Theocharis AD, Pavao MS, Tzanakakis GN, Karamanos NK: Glycosaminoglycans: key players in cancer cell biology and treatment. The FEBS journal 2012, 279(7):1177-1197. 122. Mager I, Eiriksdottir E, Langel K, El Andaloussi S, Langel U: Assessing the uptake kinetics and internalization mechanisms of cell-penetrating peptides using a quenched fluorescence assay. Biochim Biophys Acta 2010, 1798(3):338-343. 123. Barras D, Chevalier N, Zoete V, Dempsey R, Lapouge K, Olayioye MA, Michielin O, Widmann C: A WXW motif is required for the anticancer activity of the TAT-RasGAP317-326 peptide. J Biol Chem 2014, 289(34):23701-23711. 124. Walker S, Ullman O, Stultz CM: Using intramolecular disulfide bonds in tau protein to deduce structural features of aggregation-resistant conformations. J Biol Chem 2012, 287(12):9591-9600. 125. Cardin AD, Weintraub HJ: Molecular modeling of protein-glycosaminoglycan interactions. Arteriosclerosis 1989, 9(1):21-32. 126. Chen SE, Gerken E, Zhang Y, Zhan M, Mohan RK, Li AS, Reid MB, Li YP: Role of TNF-{alpha} signaling in regeneration of cardiotoxin-injured muscle. Am J Physiol Cell Physiol 2005, 289(5):C1179-1187. 127. Wu PL, Lee SC, Chuang CC, Mori S, Akakura N, Wu WG, Takada Y: Non-cytotoxic cobra cardiotoxin A5 binds to alpha(v)beta3 integrin and inhibits bone resorption. Identification of cardiotoxins as non-RGD integrin-binding proteins of the Ly-6 family. J Biol Chem 2006, 281(12):7937-7945. 128. Yu SJ, Liao EC, Sheu ML, Chang DT, Tsai JJ: Cell-penetrating peptide derived from human eosinophil cationic protein inhibits mite allergen Der p 2 induced inflammasome activation. PLoS One 2015, 10(3):e0121393. 129. Azijli K, Yuvaraj S, Peppelenbosch MP, Wurdinger T, Dekker H, Joore J, van Dijk E, Quax WJ, Peters GJ, de Jong S et al: Kinome profiling of non-canonical TRAIL signaling reveals RIP1-Src-STAT3-dependent invasion in resistant non-small cell lung cancer cells. J Cell Sci 2012, 125(Pt 19):4651-4661. 130. Liu G, Meng X, Jin Y, Bai J, Zhao Y, Cui X, Chen F, Fu S: Inhibitory role of focal adhesion kinase on anoikis in the lung cancer cell A549. Cell Biol Int 2008, 32(6):663-670. 131. Ocak S, Chen H, Callison C, Gonzalez AL, Massion PP: Expression of focal adhesion kinase in small-cell lung carcinoma. Cancer 2012, 118(5):1293-1301. 132. Kim CH, Ko AR, Lee SY, Jeon HM, Kim SM, Park HG, Han SI, Kang HS: Hypoxia switches glucose depletion-induced necrosis to phosphoinositide 3-kinase/Akt-dependent apoptosis in A549 lung adenocarcinoma cells. Int J Oncol 2010, 36(1):117-124. 133. Huttenlocher A, Horwitz AR: Integrins in cell migration. Cold Spring Harb Perspect Biol 2011, 3(9):a005074. 134. Alexandrova AY: Evolution of cell interactions with extracellular matrix during carcinogenesis. Biochemistry (Mosc) 2008, 73(7):733-741. 135. Altemeier WA, Schlesinger SY, Buell CA, Brauer R, Rapraeger AC, Parks WC, Chen P: Transmembrane and extracellular domains of syndecan-1 have distinct functions in regulating lung epithelial migration and adhesion. J Biol Chem 2012, 287(42):34927-34935. 136. Fears CY, Gladson CL, Woods A: Syndecan-2 is expressed in the microvasculature of gliomas and regulates angiogenic processes in microvascular endothelial cells. J Biol Chem 2006, 281(21):14533-14536. 137. Beauvais DM, Burbach BJ, Rapraeger AC: The syndecan-1 ectodomain regulates alphavbeta3 integrin activity in human mammary carcinoma cells. J Cell Biol 2004, 167(1):171-181. 138. Purushothaman A, Uyama T, Kobayashi F, Yamada S, Sugahara K, Rapraeger AC, Sanderson RD: Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis. Blood 2010, 115(12):2449-2457. 139. Huveneers S, Truong H, Fassler R, Sonnenberg A, Danen EH: Binding of soluble fibronectin to integrin alpha5 beta1 - link to focal adhesion redistribution and contractile shape. J Cell Sci 2008, 121(Pt 15):2452-2462. 140. Larsen M, Artym VV, Green JA, Yamada KM: The matrix reorganized: extracellular matrix remodeling and integrin signaling. Curr Opin Cell Biol 2006, 18(5):463-471. 141. Yao ES, Zhang H, Chen YY, Lee B, Chew K, Moore D, Park C: Increased beta1 integrin is associated with decreased survival in invasive breast cancer. Cancer Res 2007, 67(2):659-664. 142. Nakamura A, Osonoi T, Terauchi Y: Relationship between urinary sodium excretion and pioglitazone-induced edema. J Diabetes Investig 2010, 1(5):208-211. 143. Pikas DS, Li JP, Vlodavsky I, Lindahl U: Substrate specificity of heparanases from human hepatoma and platelets. The Journal of biological chemistry 1998, 273(30):18770-18777. 144. Vlodavsky I, Beckhove P, Lerner I, Pisano C, Meirovitz A, Ilan N, Elkin M: Significance of heparanase in cancer and inflammation. Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2012, 5(2):115-132. 145. Werb Z: ECM and cell surface proteolysis: regulating cellular ecology. Cell 1997, 91(4):439-442. 146. Carlin SM, Resink TJ, Tamm M, Roth M: Urokinase signal transduction and its role in cell migration. FASEB J 2005, 19(2):195-202. 147. Yu Q, Stamenkovic I: Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion. Genes & development 1999, 13(1):35-48. 148. Kawata M, Koinuma D, Ogami T, Umezawa K, Iwata C, Watabe T, Miyazono K: TGF-beta-induced epithelial-mesenchymal transition of A549 lung adenocarcinoma cells is enhanced by pro-inflammatory cytokines derived from RAW 264.7 macrophage cells. J Biochem 2012, 151(2):205-216. 149. Xiao D, He J: Epithelial mesenchymal transition and lung cancer. Journal of thoracic disease 2010, 2(3):154-159. 150. Hollestelle A, Peeters JK, Smid M, Timmermans M, Verhoog LC, Westenend PJ, Heine AA, Chan A, Sieuwerts AM, Wiemer EA et al: Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer. Breast cancer research and treatment 2013, 138(1):47-57. 151. Avizienyte E, Frame MC: Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition. Curr Opin Cell Biol 2005, 17(5):542-547. 152. Behr TM, Goldenberg DM, Becker W: Reducing the renal uptake of radiolabeled antibody fragments and peptides for diagnosis and therapy: present status, future prospects and limitations. European journal of nuclear medicine 1998, 25(2):201-212. 153. O'Byrne KJ, Thomas AL, Sharma RA, DeCatris M, Shields F, Beare S, Steward WP: A phase I dose-escalating study of DaunoXome, liposomal daunorubicin, in metastatic breast cancer. Br J Cancer 2002, 87(1):15-20. 154. Duncan R: Polymer conjugates as anticancer nanomedicines. Nat Rev Cancer 2006, 6(9):688-701. 155. Koren E, Torchilin VP: Cell-penetrating peptides: breaking through to the other side. Trends Mol Med 2012, 18(7):385-393. 156. Torchilin VP: Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery. Biopolymers 2008, 90(5):604-610. 157. Koren E, Apte A, Jani A, Torchilin VP: Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity. J Control Release 2012, 160(2):264-273. 158. Biswas S, Dodwadkar NS, Deshpande PP, Parab S, Torchilin VP: Surface functionalization of doxorubicin-loaded liposomes with octa-arginine for enhanced anticancer activity. Eur J Pharm Biopharm 2013, 84(3):517-525. 159. Lu RM, Chen MS, Chang DK, Chiu CY, Lin WC, Yan SL, Wang YP, Kuo YS, Yeh CY, Lo A et al: Targeted drug delivery systems mediated by a novel Peptide in breast cancer therapy and imaging. PLoS One 2013, 8(6):e66128.
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